Browsing Centre for Genomics and Child Health by Subject "2-oxoglutarate-dependent dioxygenases"
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Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation.
(2023-10-16)BACKGROUND: Vitamin C (vitC) enhances the activity of 2-oxoglutarate-dependent dioxygenases, including TET enzymes, which catalyse DNA demethylation, and Jumonji-domain histone demethylases. The epigenetic remodelling ...