Browsing Centre for Genomics and Child Health by Author "Yau, C"
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Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion
Sengupta, N; Yau, C; Sakthianandeswaren, A; Mouradov, D; Gibbs, P; Suraweera, N; Cazier, JB; Polanco-Echeverry, G; Ghosh, A; Thaha, M (2013)Prevalence of colorectal cancer (CRC) in the British Bangladeshi population (BAN) is low compared to British Caucasians (CAU). Genetic background may influence mutations and disease features. -
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
Romagnoni, A; Jegou, S; Van Steen, K; Wainrib, G; Hugot, J-P; Peyrin-Biroulet, L; Chamaillard, M; Colombel, J-F; Cottone, M; D'Amato, M (2019-07-17) -
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls
Craddock, N; Hurles, ME; Cardin, N; Pearson, RD; Plagnol, V; Robson, S; Vukcevic, D; Barnes, C; Conrad, DF; Giannoulatou, E (2010-04-01) -
Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans.
Rigoni, A; Poulsom, R; Jeffery, R; Mehta, S; Lewis, A; Yau, C; Giannoulatou, E; Feakins, R; Lindsay, JO; Colombo, MP (2017-12-19)Background: DUOX2 and DUOXA2 form the predominant H2O2-producing system in human colorectal mucosa. Inflammation, hypoxia, and 5-aminosalicylic acid increase H2O2 production, supporting innate defense and mucosal healing. ...