Browsing Centre for Genomics and Child Health by Author "Wykes, RC"
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Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models.
Tosh, JL; Rhymes, ER; Mumford, P; Whittaker, HT; Pulford, LJ; Noy, SJ; Cleverley, K; LonDownS Consortium; Walker, MC; Tybulewicz, VLJ (2021-03-11)Individuals who have Down syndrome (caused by trisomy of chromosome 21), have a greatly elevated risk of early-onset Alzheimer's disease, in which amyloid-β accumulates in the brain. Amyloid-β is a product of the chromosome ... -
Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models.
Tosh, JL; Rhymes, ER; Mumford, P; Whittaker, HT; Pulford, LJ; Noy, SJ; Cleverley, K; LonDownS Consortium; Walker, MC; Tybulewicz, VLJ (2021-07-16)