Browsing Centre for Genomics and Child Health by Author "UK10K Consortium"

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    • Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance. 

      van der Klaauw, AA; Croizier, S; Mendes de Oliveira, E; Stadler, LKJ; Park, S; Kong, Y; Banton, MC; Tandon, P; Hendricks, AE; Keogh, JM (Elsevier Inc., 2019-01-17)
      Hypothalamic melanocortin neurons play a pivotal role in weight regulation. Here, we examined the contribution of Semaphorin 3 (SEMA3) signaling to the development of these circuits. In genetic studies, we found 40 rare ...