Browsing Centre for Genomics and Child Health by Author "Rakyan, VK"
Now showing items 1-13 of 13
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Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species
Lowe, R; Barton, C; Jenkins, CA; Ernst, C; Forman, O; Fernandez-Twinn, DS; Bock, C; Rossiter, SJ; Faulkes, CG; Ozanne, SE (2018-02-16) -
Early life diet conditions the molecular response to post-weaning protein restriction in the mouse.
Danson, AF; Marzi, SJ; Lowe, R; Holland, ML; Rakyan, VK (2018-05-02)BACKGROUND: Environmental influences fluctuate throughout the life course of an organism. It is therefore important to understand how the timing of exposure impacts molecular responses. Herein, we examine the responses of ... -
eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data
Breeze, CE; Paul, DS; van Dongen, J; Butcher, LM; Ambrose, JC; Barrett, JE; Lowe, R; Rakyan, VK; Iotchkova, V; Frontini, M (2016-11-15) -
Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis
Tomazou, EM; Rakyan, VK; Lefebvre, G; Andrews, R; Ellis, P; Jackson, DK; Langford, C; Francis, MD; Backdahl, L; Miretti, M (2008-05-30) -
Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states
Rodriguez-Algarra, F; Seaborne, RAE; Danson, AF; Yildizoglu, S; Yoshikawa, H; Law, PP; Ahmad, Z; Maudsley, VA; Brew, A; Holmes, N (2022) -
Genome Wide Analysis of Acute Myeloid Leukemia Reveal Leukemia Specific Methylome and Subtype Specific Hypomethylation of Repeats
Saied, MH; Marzec, J; Khalid, S; Smith, P; Down, TA; Rakyan, VK; Molloy, G; Raghavan, M; Debernardi, S; Young, BD (2012-03-29) -
Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
Bell, CG; Teschendorff, AE; Rakyan, VK; Maxwell, AP; Beck, S; Savage, DA (2010-08-05) -
Identification of Type 1 Diabetes-Associated DNA Methylation Variable Positions That Precede Disease Diagnosis
Rakyan, VK; Beyan, H; Down, TA; Hawa, MI; Maslau, S; Aden, D; Daunay, A; Busato, F; Mein, CA; Manfras, B (2011-09) -
Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
Thurner, M; van de Bunt, M; Torres, JM; Mahajan, A; Nylander, V; Bennett, AJ; Gaulton, KJ; Barrett, A; Burrows, C; Bell, CG (2018-02-07) -
Marmal-aid - a database for Infinium HumanMethylation450
Lowe, R; Rakyan, VK (2013-12-12) -
Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates
Hillman, SL; Finer, S; Smart, MC; Mathews, C; Lowe, R; Rakyan, VK; Hitman, GA; Williams, DJ (2015-01) -
Ribosomal DNA copy number variation associates with hematological profiles and renal function in the UK Biobank.
Rodriguez-Algarra, F; Evans, DM; Rakyan, VK (2024-05-10)The phenotypic impact of genetic variation of repetitive features in the human genome is currently understudied. One such feature is the multi-copy 47S ribosomal DNA (rDNA) that codes for rRNA components of the ribosome. ... -
Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development
Lowe, R; Gemma, C; Rakyan, VK; Holland, ML (2015-04-14)