Browsing Centre for Genomics and Child Health by Author "Lai, C-F"
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LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.
Kramer, HB; Lai, C-F; Patel, H; Periyasamy, M; Lin, M-L; Feller, SM; Fuller-Pace, FV; Meek, DW; Ali, S; Buluwela, L (2016-01-29)Liver receptor homologue 1 (LRH-1) is an orphan nuclear receptor that has been implicated in the progression of breast, pancreatic and colorectal cancer (CRC). To determine mechanisms underlying growth promotion by LRH-1 ...