Browsing Centre for Genomics and Child Health by Author "Danial, JSH"
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Cerebral organoids with chromosome 21 trisomy secrete Alzheimer's disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy
Fertan, E; Böken, D; Murray, A; Danial, JSH; Lam, JYL; Wu, Y; Goh, PA; Alić, I; Cheetham, MR; Lobanova, E (Springer Nature, 2023-12-15)Understanding the role of small, soluble aggregates of beta-amyloid (Aβ) and tau in Alzheimer's disease (AD) is of great importance for the rational design of preventative therapies. Here we report a set of methods for the ...