Browsing Centre for Genomics and Child Health by Author "Danesh, J"
Now showing items 1-7 of 7
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Association analyses based on false discovery rate implicate new loci for coronary artery disease
Nelson, CP; Goel, A; Butterworth, AS; Kanoni, S; Webb, TR; Marouli, E; Zeng, L; Ntalla, I; Lai, FY; Hopewell, JC (2017-09) -
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease
Nikpay, M; Goel, A; Won, H-H; Hall, LM; Willenborg, C; Kanoni, S; Saleheen, D; Kyriakou, T; Nelson, CP; Hopewell, JC (2015-10) -
Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.
Corbin, LJ; Tan, VY; Hughes, DA; Wade, KH; Paul, DS; Tansey, KE; Butcher, F; Dudbridge, F; Howson, JM; Jallow, MW (2018-02-19)Detailed phenotyping is required to deepen our understanding of the biological mechanisms behind genetic associations. In addition, the impact of potentially modifiable risk factors on disease requires analytical frameworks ... -
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Suzuki, K; Hatzikotoulas, K; Southam, L; Taylor, HJ; Yin, X; Lorenz, KM; Mandla, R; Huerta-Chagoya, A; Melloni, GEM; Kanoni, S (Nature Research, 2024-02-19)Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic contribution ... -
Mapping the human genetic architecture of COVID-19
Niemi, MEK; Karjalainen, J; Daly, M; Ganna, A; Mehtonen, J; Cordioli, M; Kaunisto, M; Pigazzini, S; Donner, K; Kivinen, K (2021) -
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity
Hendricks, AE; Bochukova, EG; Marenne, G; Keogh, JM; Atanassova, N; Bounds, R; Wheeler, E; Mistry, V; Henning, E; Koerner, A (2017-06-29) -
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations
Chen, M-H; Raffield, LM; Mousas, A; Sakaue, S; Huffman, JE; Moscati, A; Trivedi, B; Jiang, T; Akbari, P; Vuckovic, D (2020-09-03)