Browsing Centre for Genomics and Child Health by Title
Now showing items 820-835 of 835
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Virological response and resistance among HIV-infected children receiving long-term antiretroviral therapy without virological monitoring in Uganda and Zimbabwe: Observational analyses within the randomised ARROW trial.
(2017-11)BACKGROUND: Although WHO recommends viral load (VL) monitoring for those on antiretroviral therapy (ART), availability in low-income countries remains limited. We investigated long-term VL and resistance in HIV-infected ... -
Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation.
(2023-10-16)BACKGROUND: Vitamin C (vitC) enhances the activity of 2-oxoglutarate-dependent dioxygenases, including TET enzymes, which catalyse DNA demethylation, and Jumonji-domain histone demethylases. The epigenetic remodelling ... -
Vitamin D3 and B12 Supplementation in Pregnancy.
(Elsevier, 2021-03-01)AIM: To assess the efficacy of vitamin D3 or B12 supplementation during pregnancy. METHODS: Pregnant women at 6-14 weeks in the intervention arm received oral high dose intermittent vitamin D3 and/or low dose B12 supplementation ... -
The WASH Benefits and SHINE Trials. Interpretation of Findings on Linear Growth and Diarrhoea and Implications for Policy: Perspective of the Investigative Teams (P10-136-19).
(2019-06)Objectives: We recently completed 3 efficacy trials (Bangladesh, Kenya, Zimbabwe) testing the independent and combined effects of improved complementary feeding (CF) and intensive household water quality, sanitation, and ... -
Water, sanitation and hygiene (WASH) interventions: Effects on child development in low- and middle-income countries
(2017-03-30)© 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: Main objective: The main objective is to assess the effect of ... -
Where Do Inhaled Fossil Fuel-derived Particles Go?
(2017-10-01) -
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases
(2015-08-27)© 2015 Nature America, Inc. All rights reserved. Human leukocyte antigen (HLA) genes confer substantial risk for autoimmune diseases on a log-additive scale. Here we speculated that differences in autoantigen-binding ... -
World No Tobacco Day: smoking, nicotine and children
(European Respiratory Society, 2020-05-27) -
Zebrafish Fukutin family proteins link the unfolded protein response with dystroglycanopathies.
(2011-05-01)Allelic mutations in putative glycosyltransferase genes, fukutin and fukutin-related protein (fkrp), lead to a wide range of muscular dystrophies associated with hypoglycosylation of α-dystroglycan, commonly referred to ...
