Browsing Centre for Genomics and Child Health by Title
Now showing items 689-708 of 835
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Reduced bacterial skin infections in HIV-infected African children randomized to long-term cotrimoxazole prophylaxis
(Wolters Kluwer Health, Inc, 2016-11-28)Objective: To evaluate whether cotrimoxazole prophylaxis prevents common skin conditions in HIV-infected children. Design: Open-label randomized controlled trial of continuing versus stopping daily cotrimoxazole ... -
Regional differences in short stature in England between 2006 and 2019: A cross-sectional analysis from the National Child Measurement Programme.
(Public Library of Science, 2021-09-28)BACKGROUND: Short stature, defined as height for age more than 2 standard deviations (SDs) below the population median, is an important indicator of child health. Short stature (often termed stunting) has been widely ... -
Reply.
(2017-07) -
A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome
(Springer Nature, 2020-01-17)Purpose: To investigate if specific exon 38 or 39 KMT2D missense variants (MVs) cause a condition distinct from Kabuki syndrome type 1 (KS1). Methods: Multiple individuals, with MVs in exons 38 or 39 of KMT2D that ... -
Revision of RUNX1 variant curation rules.
(2022-08-23) -
Ribosomal DNA copy number variation associates with hematological profiles and renal function in the UK Biobank.
(2024-05-10)The phenotypic impact of genetic variation of repetitive features in the human genome is currently understudied. One such feature is the multi-copy 47S ribosomal DNA (rDNA) that codes for rRNA components of the ribosome. ... -
Risk of pneumonia in obstructive lung disease: A real-life study comparing extra-fine and fine-particle inhaled corticosteroids.
(2017)BACKGROUND: Regular use of inhaled corticosteroids (ICS) in patients with obstructive lung diseases has been associated with a higher risk of pneumonia, particularly in COPD. The risk of pneumonia has not been previously ... -
Role for extracellular vesicles in the tumour microenvironment.
(2018-01-05)Extracellular vesicles (EVs) are small-membrane vesicles secreted by most cells types with the role to provide intercellular communication both locally and systemically. The transfer of their content between cells, which ...