Browsing Centre for Genomics and Child Health by Title
Now showing items 497-516 of 835
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LGG-57. SIGNALLING MECHANISMS IN PAEDIATRIC LOW-GRADE GLIOMA
(Oxford University Press on behalf of the Society for Neuro-Oncology., 2020-12-04)Abstract LGG-57 from the 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020) -
LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions.
(BioMed Central, 2021-02-18)BACKGROUND: To investigate the mechanisms driving regulatory evolution across tissues, we experimentally mapped promoters, enhancers, and gene expression in the liver, brain, muscle, and testis from ten diverse mammals. ... -
LiquidCNA: tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations
(2021)Cell-free DNA (cfDNA) measured via liquid biopsies provides a way for minimally-invasive monitoring of tumour evolutionary dynamics during therapy. Here we present liquidCNA, a method to track subclonal evolution from ... -
Local action on outdoor air pollution to improve public health.
(2018-06)OBJECTIVES: The National Institute for Health and Care Excellence, jointly with Public Health England, have developed a guideline on outdoor air pollution and its links to health. The guideline makes recommendations on ... -
Locomotion system for a medical device
(Patent Application Publication, 2024-01-25)A locomotion system for use in a medical device, including at least one magnet, a rotor including a plurality of coil windings, and a ferromagnetic member. The rotor is configured, on application of a current to the plurality ... -
Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders.
(MDPI, 2021-06-17)Development is a complex process regulated both by genetic and epigenetic and environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key regulators of gene expression in several tissues including the ... -
Long tails, short telomeres: Dyskeratosis congenita
(2015-06-10) -
LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.
(2016-01-29)Liver receptor homologue 1 (LRH-1) is an orphan nuclear receptor that has been implicated in the progression of breast, pancreatic and colorectal cancer (CRC). To determine mechanisms underlying growth promotion by LRH-1 ...