Browsing Centre for Cell Biology and Cutaneous Research by Subject "Up-Regulation"
Now showing items 1-3 of 3
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Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity.
(2017-11)BACKGROUND: Upregulation of kallikreins (KLKs) including KLK5 has been reported in atopic dermatitis (AD). KLK5 has biological functions that include degrading desmosomal proteins and inducing proinflammatory cytokine ... -
Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16.
(2017-01-27)Keratin 16 (K16) is a cytoskeletal scaffolding protein highly expressed at pressure-bearing sites of the mammalian footpad. It can be induced in hyperproliferative states such as wound healing, inflammation and cancer. ... -
T-cell reconstitution after thymus xenotransplantation induces hair depigmentation and loss.
(2013-05)Here we present a mouse model for T-cell targeting of hair follicles, linking the pathogenesis of alopecia to that of depigmentation disorders. Clinically, thymus transplantation has been successfully used to treat T-cell ...