Browsing Centre for Cell Biology and Cutaneous Research by Subject "T cells"

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    • Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation. 

      Papaioannou, E; Yánez, DC; Ross, S; Lau, C-I; Solanki, A; Chawda, MM; Virasami, A; Ranz, I; Ono, M; O'Shaughnessy, RFL (2019-07-02)
      Hedgehog (Hh) proteins regulate development and tissue homeostasis, but their role in atopic dermatitis (AD) remains unknown. We found that on induction of mouse AD, Sonic Hedgehog (Shh) expression in skin, and Hh pathway ...