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dc.contributor.authorDobson, R
dc.contributor.authorDassan, P
dc.contributor.authorRoberts, M
dc.contributor.authorGiovannoni, G
dc.contributor.authorNelson-Piercy, C
dc.contributor.authorBrex, PA
dc.date.accessioned2019-02-04T11:50:22Z
dc.date.available2018-11-01
dc.date.available2019-02-04T11:50:22Z
dc.date.issued2019-01-05
dc.identifier.issn1474-7758
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/55128
dc.description.abstractMultiple sclerosis (MS) is more common in women than men and is most commonly diagnosed in early adulthood; thus, many patients will not have completed their families at the time of diagnosis. There is increasing awareness of the importance of early treatment in preventing long-term disability in MS. Delaying treatment until women with MS have completed their families can lead to the development of irreversible disability in at least some cases. It is therefore important to discuss family planning and pregnancy proactively. However, to date there is limited evidence to inform such discussions. We set out to develop consensus guidelines for the treatment of MS in pregnancy to encourage and facilitate discussions in this important area. The guidelines draw on available evidence from drug-specific pregnancy registers and published literature and have been scored by a panel of experts from a variety of disciplines using modified Delphi criteria. They cover prepregnancy counselling, management during pregnancy, delivery and anaesthetic options, postpartum advice and specific advice regarding currently licensed disease-modifying drugs. As the complexity and range of available disease-modifying drugs increase, further data gathering via a UK-wide MS pregnancy register is recommended.en_US
dc.description.sponsorshipMS Trust
dc.languageeng
dc.language.isoenen_US
dc.relation.ispartofPract Neurol
dc.rightsAttribution-NonCommercial-NoDerivs
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/
dc.subjectdisease modifying therapyen_US
dc.subjectmultiple sclerosisen_US
dc.subjectpregnancyen_US
dc.titleUK consensus on pregnancy in multiple sclerosis: 'Association of British Neurologists' guidelines.en_US
dc.typeArticleen_US
dc.identifier.doi10.1136/practneurol-2018-002060
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/30612100en_US
pubs.notesNot knownen_US
pubs.publication-statusPublished onlineen_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US


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