Potassium channels in the sinoatrial node and their role in heart rate control.
View/ Open
Volume
12
Pagination
356 - 366
DOI
10.1080/19336950.2018.1532255
Journal
Channels (Austin)
Issue
Metadata
Show full item recordAbstract
Potassium currents determine the resting membrane potential and govern repolarisation in cardiac myocytes. Here, we review the various currents in the sinoatrial node focussing on their molecular and cellular properties and their role in pacemaking and heart rate control. We also describe how our recent finding of a novel ATP-sensitive potassium channel population in these cells fits into this picture.
Authors
Aziz, Q; Li, Y; Tinker, AURI
https://www.tandfonline.com/doi/pdf/10.1080/19336950.2018.1532255?needAccess=truehttp://qmro.qmul.ac.uk/xmlui/handle/123456789/48005