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dc.contributor.authorPereira, SSen_US
dc.contributor.authorKempley, STen_US
dc.contributor.authorShah, DKen_US
dc.contributor.authorMorris, JKen_US
dc.contributor.authorSinha, AKen_US
dc.date.accessioned2018-10-05T13:20:43Z
dc.date.available2018-04-09en_US
dc.date.issued2018-11en_US
dc.date.submitted2018-04-26T07:43:10.478Z
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/45948
dc.description.abstractAIM: To determine whether early echocardiographic ductal parameters identified infants who subsequently received medical or surgical treatment of the patent ductus arteriosus (PDA). METHODS: Infants <29 weeks had PDA size in 2D and colour, flow velocity and patterns obtained on days 1 and 3. Infants were followed up to identify those subsequently receiving treatment for symptomatic PDA by clinicians who were unaware of scan results. Receiver operator characteristics curves and logistic regression were performed. RESULTS: Sixty infants were studied. Mean (SD) gestation and birthweight were 25.8 (1.5) weeks and 817 (190) grams, respectively. Twenty-four (40%) infants received medical treatment, and nine (15%) infants received surgical ligation of PDA at a median age of 12 and 37 days, respectively. PDA size on days 1 and 3, change in ductal size between days 1 and 3, flow pattern/velocity did not predict whether infants subsequently received medical or surgical management of PDA. Using logistic regression, gestation (p = 0.006) was the only factor that predicted whether infants would subsequently receive medical or surgical treatment for PDA in this cohort. CONCLUSION: Echocardiographic ductal parameters on day 1 or 3 did not identify infants who received PDA treatment. Gestation was the most powerful predictor for receiving medical or surgical treatment of PDA.en_US
dc.format.extent1909 - 1916en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofActa Paediatren_US
dc.subjectEchocardiographyen_US
dc.subjectPDA treatmenten_US
dc.subjectPatent ductus arteriosusen_US
dc.subjectPreterm infanten_US
dc.titleEarly echocardiography does not predict subsequent treatment of symptomatic patent ductus arteriosus in extremely preterm infants.en_US
dc.typeArticle
dc.identifier.doi10.1111/apa.14361en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/29663524en_US
pubs.issue11en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume107en_US
dcterms.dateAccepted2018-04-09en_US


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