Centre for Endocrinology: Recent submissions
Now showing items 21-40 of 560
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Effects of the COVID-19 pandemic on the incidence of central precocious puberty; a narrative review.
(2024-02-26)Central precocious puberty (CPP) is the premature activation of the hypothalamus-pituitary-gonadal axis, resulting in the early development of secondary sexual characteristics. CPP classically occurs before the age of 8 ... -
Outcomes and experiences of adults with congenital hypogonadism can inform improvements in the management of delayed puberty.
(2024-01-29)Patients with congenital hypogonadism will encounter many health care professionals during their lives managing their health needs; from antenatal and infantile periods, through childhood and adolescence, into adult life ... -
Gonadotropins for pubertal induction in males with hypogonadotropic hypogonadism: systematic review and meta-analysis.
(2024-01-03)OBJECTIVE: Hypogonadotropic hypogonadism is characterized by inadequate secretion of pituitary gonadotropins, leading to absent, partial, or arrested puberty. In males, classical treatment with testosterone promotes ... -
Translating the potential of the urine steroid metabolome to stage NAFLD (TrUSt-NAFLD): study protocol for a multicentre, prospective validation study.
(2024-01-18)INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) affects approximately one in four individuals and its prevalence continues to rise. The advanced stages of NAFLD with significant liver fibrosis are associated with ... -
SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability.
(Nature Research, 2023-12-07)Innervation of the hypothalamic median eminence by Gonadotropin-Releasing Hormone (GnRH) neurons is vital to ensure puberty onset and successful reproduction. However, the molecular and cellular mechanisms underlying median ... -
MesoGraph: Automatic profiling of mesothelioma subtypes from histological images.
(2023-10-05)Mesothelioma is classified into three histological subtypes, epithelioid, sarcomatoid, and biphasic, according to the relative proportions of epithelioid and sarcomatoid tumor cells present. Current guidelines recommend ... -
THU079 Danio Rerio (Zebrafish): A New Model Of AIP Loss Of Function
(The Endocrine Society, 2023-10-05) -
National UK guidelines for the management of paediatric craniopharyngioma.
(2023-09)Although rare, craniopharyngiomas constitute up to 80% of tumours in the hypothalamic-pituitary region in childhood. Despite being benign, the close proximity of these tumours to the visual pathways, hypothalamus, and ... -
Effective Long-term Pediatric Pegvisomant Monotherapy to Final Height in X-linked Acrogigantism
(The Endocrine Society, 2023-05-08)