Browsing Centre for Endocrinology by Author "Saeger, W"
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From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal.
Asa, SL; Casar-Borota, O; Chanson, P; Delgrange, E; Earls, P; Ezzat, S; Grossman, A; Ikeda, H; Inoshita, N; Karavitaki, N (2017-04)The classification of neoplasms of adenohypophysial cells is misleading because of the simplistic distinction between adenoma and carcinoma, based solely on metastatic spread and the poor reproducibility and predictive ... -
Novel AIP mutation in exon 6 causing acromegaly in a German family.
Detomas, M; Altieri, B; Flitsch, J; Saeger, W; Korbonits, M; Deutschbein, T (2023-08)The most frequent genetic alteration of familial isolated growth hormone producing pituitary neuroendocrine tumors is a germline mutation of the aryl hydrocarbon receptor-interacting protein (AIP) gene. Various AIP mutations ... -
Somatic USP8 mutations are frequent events in corticotroph tumor progression causing Nelson's tumor.
Pérez-Rivas, LG; Theodoropoulou, M; Puar, TH; Fazel, J; Stieg, MR; Ferraù, F; Assié, G; Gadelha, MR; Deutschbein, T; Fragoso, MC (2018-01)OBJECTIVE: Somatic mutations in the ubiquitin-specific protease 8 (USP8) gene are frequent in corticotroph tumors causing Cushing's disease (CD). Corticotroph tumor progression, the so-called Nelson's syndrome (NS), is a ...