Browsing Centre for Endocrinology by Author "Jacques, TS"
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Consensus guideline for the diagnosis and management of pituitary adenomas in childhood and adolescence: Part 2, specific diseases.
Korbonits, M; Blair, JC; Boguslawska, A; Ayuk, J; Davies, JH; Druce, MR; Evanson, J; Flanagan, D; Glynn, N; Higham, CE (2024-02-09)Pituitary adenomas are rare in children and young people under the age of 19 (hereafter referred to as CYP) but they pose some different diagnostic and management challenges in this age group than in adults. These rare ... -
Consensus guideline for the diagnosis and management of pituitary adenomas in childhood and adolescence: Part 1, general recommendations.
Korbonits, M; Blair, JC; Boguslawska, A; Ayuk, J; Davies, JH; Druce, MR; Evanson, J; Flanagan, D; Glynn, N; Higham, CE (2024-02-09)Tumours of the anterior part of the pituitary gland represent just 1% of all childhood (aged <15 years) intracranial neoplasms, yet they can confer high morbidity and little evidence and guidance is in place for their ... -
Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma
Andoniadou, CL; Gaston-Massuet, C; Reddy, R; Schneider, RP; Blasco, MA; Le Tissier, P; Jacques, TS; Pevny, LH; Dattani, MT; Martinez-Barbera, JP (2012-02-18) -
National UK guidelines for the management of paediatric craniopharyngioma.
Gan, H-W; Morillon, P; Albanese, A; Aquilina, K; Chandler, C; Chang, Y-C; Drimtzias, E; Farndon, S; Jacques, TS; Korbonits, M (2023-09)Although rare, craniopharyngiomas constitute up to 80% of tumours in the hypothalamic-pituitary region in childhood. Despite being benign, the close proximity of these tumours to the visual pathways, hypothalamus, and ... -
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Apps, JR; Carreno, G; Gonzalez-Meljem, JM; Haston, S; Guiho, R; Cooper, JE; Manshaei, S; Jani, N; Hölsken, A; Pettorini, B (2018-05)Adamantinomatous craniopharyngiomas (ACPs) are clinically challenging tumours, the majority of which have activating mutations in CTNNB1. They are histologically complex, showing cystic and solid components, the latter ...