Browsing Centre for Endocrinology by Author "Fantin, A"
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HS6ST1 Insufficiency Causes Self-Limited Delayed Puberty in Contrast With Other GnRH Deficiency Genes.
Howard, SR; Oleari, R; Poliandri, A; Chantzara, V; Fantin, A; Ruiz-Babot, G; Metherell, LA; Cabrera, CP; Barnes, MR; Wehkalampi, K (2018-09-01)Context: Self-limited delayed puberty (DP) segregates in an autosomal-dominant pattern, but the genetic basis is largely unknown. Although DP is sometimes seen in relatives of patients with hypogonadotropic hypogonadism ... -
SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability.
Lettieri, A; Oleari, R; van den Munkhof, MH; van Battum, EY; Verhagen, MG; Tacconi, C; Spreafico, M; Paganoni, AJJ; Azzarelli, R; Andre', V (Nature Research, 2023-12-07)Innervation of the hypothalamic median eminence by Gonadotropin-Releasing Hormone (GnRH) neurons is vital to ensure puberty onset and successful reproduction. However, the molecular and cellular mechanisms underlying median ...