Now showing items 1-5 of 5
Characterisation of myocardial structure and function in adult-onset growth hormone deficiency using cardiac magnetic resonance.
Growth hormone (GH) can profoundly influence cardiac function. While GH excess causes well-defined cardiac pathology, fewer data are available regarding the more subtle cardiac changes seen in GH deficiency (GHD). This ...
Patient-reported outcomes of parenteral somatostatin analogue injections in 195 patients with acromegaly.
BACKGROUND: Long-acting somatostatin analogues delivered parenterally are the most widely used medical treatment in acromegaly. This patient-reported outcomes survey was designed to assess the impact of chronic injections ...
Metformin prevents metabolic side effects during systemic glucocorticoid treatment.
OBJECTIVES: Patients receiving glucocorticoid treatment are prone to develop metabolic complications. In preclinical studies, metformin prevented the development of the metabolic syndrome during glucocorticoid excess. We ...
Renin-Angiotensin System Blockade Improves Cardiac Indices in Acromegaly Patients.
Blockade of the angiotensin-renin system, with angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs), has been shown to improve cardiac outcomes following myocardial infarction and delay ...