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Generation of Recombinant Monoclonal Antibodies from Single B Cells Isolated from Synovial Tissue of Rheumatoid Arthritis Patients.
(Humana Press, 2018-08-24)
Ectopic lymphoid structure (ELS) can form in the target tissues of patients with chronic inflammatory autoimmune diseases such as rheumatoid arthritis (RA) and Sjögren's syndrome (SS). Although it is still not clear why ...
RA SYNOVIAL RECOMBINANT MONOCLONAL ANTIBODIES FROM SINGLE B CELLS TARGET CITRULLINATED CALRETICULIN
(2017-03-01)
Meeting abstract 08.34 from 37th European Workshop on Rheumatology Research (EWRR) Athens, GREECE, MAR 02-04, 2017
Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren's syndrome with ectopic germinal centres and MALT lymphoma.
(2020-09-22)
OBJECTIVES: To explore the relevance of T-follicular-helper (Tfh) and pathogenic peripheral-helper T-cells (Tph) in promoting ectopic lymphoid structures (ELS) and B-cell mucosa-associated lymphoid tissue (MALT) lymphomas ...