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Now showing items 81-90 of 136
Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients.
(Public Library of Science, 2021-08-26)
Coronavirus disease (COVID)-19, as a result of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, has been the direct cause of over 2.2 million deaths worldwide. A timely coordinated host-immune response ...
Reintroduction of elective cardiac interventions in the era of COVID-19: the Barts experience.
(2021-04)
BACKGROUND: The response to COVID-19 has required cancellation of all but the most urgent procedures; there is therefore a need for the reintroduction of a safe elective pathway. METHODS: This was a study of a pilot pathway ...
An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.
(2014-03)
The phagocytosis of apoptotic cells (ACs), or efferocytosis, by DCs is critical for self-tolerance and host defense. Although many efferocytosis-associated receptors have been described in vitro, the functionality of these ...
Association of different antiplatelet therapies with mortality after primary percutaneous coronary intervention.
(2018-10)
OBJECTIVES: Prasugrel and ticagrelor both reduce ischaemic endpoints in high-risk acute coronary syndromes, compared with clopidogrel. However, comparative outcomes of these two newer drugs in the context of primary ...
A Study of Platelet Inhibition, Using a 'Point of Care' Platelet Function Test, following Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction [PINPOINT-PPCI].
(2015)
BACKGROUND: Rapid coronary recanalization following ST-elevation myocardial infarction (STEMI) requires effective anti-platelet and anti-thrombotic therapies. This study tested the impact of door to end of procedure ...
Effects of vitamin D supplementation on upper and lower body muscle strength levels in healthy individuals. A systematic review with meta-analysis.
(2015-09)
OBJECTIVES: To investigate the effects of vitamin D supplementation on muscle strength in healthy individuals. DESIGN: A systematic review with meta-analysis. METHODS: In October 2013 a computerised literature search of ...
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
(Nature Research, 2021-01-05)
Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in ...
Intravascular multimodality imaging: feasibility and role in the evaluation of coronary plaque pathology.
(Oxford University Press, 2017-02-17)
Coronary artery disease remains the leading cause of death in the developed world. Over recent years, research has been focused on the development of diagnostic intravascular imaging techniques that enable assessment of ...
How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project).
(2018-08-14)
OBJECTIVES: To evaluate the influence of the main immunological markers on the disease phenotype at diagnosis in a large international cohort of patients with primary Sjögren's syndrome (SjS). METHODS: The Big Data Sjögren ...