Browsing Blizard Institute by Subject "Obesity"
Now showing items 1-15 of 15
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Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
(2009-02)OBJECTIVE: This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes association and considered the implications for the etiological ... -
Are children living with obesity more likely to experience musculoskeletal symptoms during childhood? A linked longitudinal cohort study using primary care records.
(2024-03-12)OBJECTIVE: To assess whether there is a higher incidence of musculoskeletal consultations in general practice among children with obesity. DESIGN: Longitudinal SETTING: 285 north-east London general practitioners (GPs). ... -
Community pharmacy interventions for public health priorities: protocol for a systematic review of community pharmacy-delivered smoking, alcohol and weight management interventions.
(2014-08-22)BACKGROUND: Community pharmacists can deliver health care advice at an opportunistic level, related to prescription or non-prescription medicines and as part of focused services designed to reduce specific risks to health. ... -
Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety.
(2017-11)OBJECTIVE: Genetic studies in obese rodents and humans can provide novel insights into the mechanisms involved in energy homeostasis. METHODS: In this study, we genetically mapped the chromosomal region underlying the ... -
Effectiveness of eHealth weight management interventions in overweight and obese adults from low socioeconomic groups: a systematic review.
(2023-03-30)BACKGROUND: Low socioeconomic status (SES) is associated with increased rates of overweight and obesity. Proponents of electronic health (eHealth) hypothesise that its inclusion in weight management interventions can improve ... -
Excess Gestational Weight Gain in Pregnancy and the Role of Lifestyle Intervention.
(2016-03)With increasingly adverse lifestyles, young women in many countries have rapid weight gain and rising obesity. In keeping with this, most pregnant women exceed recommended gestational weight gain (GWG) and then retain ... -
Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota.
(2018-05-24)BACKGROUND: The early-life gut microbiota plays a critical role in host metabolism in later life. However, little is known about how the fatty acid profile of the maternal diet during gestation and lactation influences the ... -
Mediterranean diet based intervention in pregnancy to improve maternal and fetal outcomes: Methodological challenges and lessons learned from the multicentre ESTEEM study.
(2017-06)Introduction: Evaluating complex dietary interventions such as Mediterranean diet in pregnancy presents unique methodological challenges. We present the challenges and the lessons learned from a multicentre randomised trial ... -
Randomised controlled trial and economic evaluation of a task-based weight management group programme.
(2019-04-02)BACKGROUND: Obesity is a rising global threat to health and a major contributor to health inequalities. Weight management programmes that are effective, economical and reach underprivileged groups are needed. We examined ... -
Severe obesity and diabetes insipidus in a patient with PCSK1 deficiency
(Elsevier, 2013) -
Transcriptomics of the Prader-Willi syndrome hypothalamus.
(2021)Prader-Willi syndrome (PWS) is a complex neurodevelopmental disorder, arising from a loss of paternity expressed genetic material on the imprinted chromosome locus 15q11-q13. Despite increasing clarity on the underlying ... -
Weight variability and cardiovascular outcomes: a systematic review and meta-analysis
(BMC, 2023-01-09)The association between body weight variability and the risk of cardiovascular disease (CVD) has been investigated previously with mixed findings. However, there has been no extensive study which systematically evaluates ...