Browsing Blizard Institute by Subject "B cells"
Now showing items 1-9 of 9
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B cells defined by immunoglobulin isotypes
(Oxford University Press, 2022-10-05) -
Circulating and intrahepatic antiviral B cells are defective in hepatitis B.
(American Society for Clinical Investigation, 2018-08-09)B cells are increasingly recognized as playing an important role in the ongoing control of hepatitis B virus (HBV). The development of antibodies against the viral surface antigen (HBV surface antigen [HBsAgs]) constitutes ... -
PD-1 blockade partially recovers dysfunctional virus-specific B cells in chronic hepatitis B infection.
(2018-10-01)Chronic HBV (CHB) infection suppresses virus-specific T cells, but its impact on humoral immunity has been poorly analyzed. Here, we developed a dual-staining method that utilizes hepatitis B virus (HBV) surface antigens ... -
Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease.
(Wiley, 2024-04-29)Single cell RNA sequencing of human full thickness Crohn's disease (CD) small bowel resection specimens was used to identify potential therapeutic targets for stricturing (S) CD. Using an unbiased approach, 16 cell lineages ... -
Single-cell RNA sequencing reveals the expansion of circulating tissue-homing B cell subsets in secondary acute dengue viral infection.
(Elsevier, 2024-05-30)The roles of antibodies secreted by subsets of B cells in dengue virus (DENV) infection have been extensively studied, yet, the contribution of tissue-homing B cells to antiviral immunity remains unclear. In this study, ...