Browsing Centre for Cell Signalling by Title
Now showing items 1-17 of 17
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Cell death pathways and autophagy in the central nervous system and its involvement in neurodegeneration, immunity and central nervous system infection: to die or not to die - that is the question
(2012-04)Death rules our lives. In this short paper, we summarize new insights into molecular mechanisms of neurodegeneration. Here we review the most important processes of cell death: apoptosis and oncosis. We focus on autophagy, ... -
Cerebrospinal fluid HIV RNA escape symptomatology.
(2021-06-15)OBJECTIVE: To characterise the clinical, laboratory and radiological characteristics of persons with HIV (PWH) presenting with cerebrospinal fluid (CSF) HIV RNA escape. DESIGN: Retrospective case review of PWH presenting ... -
Hallmarks of cancer stem cell metabolism.
(2016-06-14)Cancer cells adapt cellular metabolism to cope with their high proliferation rate. Instead of primarily using oxidative phosphorylation (OXPHOS), cancer cells use less efficient glycolysis for the production of ATP and ... -
Investigating the impact of London's ultra low emission zone on children's health: children's health in London and Luton (CHILL) protocol for a prospective parallel cohort study.
(2023-11-04)BACKGROUND: Air pollution harms health across the life course. Children are at particular risk of adverse effects during development, which may impact on health in later life. Interventions that improve air quality are ... -
The melanocortin receptors and their accessory proteins.
(2013)The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function. Since their ... -
Nano-volume well array chip for large-scale propagation and high-resolution analysis of individual cancer stem cells
(OMICS Publishing Group, 2014)Cellular heterogeneity represents an increasingly appreciated aspect for research in life science. To address this issue, we have developed a nano-volume well array chip that allows larger-scale isolation and propagation ...
