Browsing Barts Cancer Institute by Subject "tumour microenvironment"
Now showing items 1-5 of 5
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Inter- and intra-tumoural heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma.
(Wiley Online, 2018-12-21)Cancer-associated fibroblasts (CAF) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Stromal heterogeneity may explain differential pathophysiological roles of the stroma (pro- versus ... -
Reflected stemness as a potential driver of the tumour microenvironment
(2022-12)A fundamental requirement for cancer initiation is the activation of developmental programmes by mutant cells. Oncogenic signals often confer an undifferentiated, stem cell-like phenotype that supports the long-term ... -
Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer.
(2021)A growing body of literature links events associated with the progression and severity of immunity and inflammatory disease with the composition of the tissue extracellular matrix as defined by the matrisome. One protein ...