Browsing Barts Cancer Institute by Subject "mathematical modeling"

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    • The 2019 Mathematical Oncology Roadmap. 

      Rockne, RC; Hawkins-Daarud, A; Swanson, KR; Sluka, JP; Glazier, JA; Macklin, P; Hormuth, D; Jarrett, AM; Lima, EABDF; Oden, J (IOP Publishing, 2019-04-16)
      Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology, Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is no denying that mathematics continues to ...

    • Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches. 

      Byrne, KM; Monsefi, N; Dawson, JC; Degasperi, A; Bukowski-Wills, J-C; Volinsky, N; Dobrzyński, M; Birtwistle, MR; Tsyganov, MA; Kiyatkin, A (2016-01-27)
      Dynamic interactions between RhoA and Rac1, members of the Rho small GTPase family, play a vital role in the control of cell migration. Using predictive mathematical modeling, mass spectrometry-based quantitation of network ...