Browsing Barts Cancer Institute by Subject "liver metastases"

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    • Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma. 

      Raj, D; Yang, M-H; Rodgers, D; Hampton, EN; Begum, J; Mustafa, A; Lorizio, D; Garces, I; Propper, D; Kench, JG (2018-08-18)
      OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is a disease of unmet medical need. While immunotherapy with chimeric antigen receptor T (CAR-T) cells has shown much promise in haematological malignancies, their efficacy ...