Browsing Barts Cancer Institute by Subject "Molecular Targeted Therapy"
Now showing items 1-3 of 3
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Cdk7: open questions beyond the prevailing model.
(2012-10-01) -
Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma.
(2018-07)BACKGROUND: Existing preclinical murine models often fail to predict effects of anti-cancer drugs. In order to minimize interspecies-differences between murine hosts and human bone tumors of in vivo xenograft platforms, ... -
Unravelling the pharmacologic opportunities and future directions for targeted therapies in gastro-intestinal cancers part 2: Neuroendocrine tumours, hepatocellular carcinoma, and gastro-intestinal stromal tumours.
(2018-01)Until the 1990s, cytotoxic chemotherapy has been the cornerstone of medical therapy for gastrointestinal (GI) cancers. Better understanding of the cancer cell molecular biology has led to the therapeutic revolution of ...