Browsing Barts Cancer Institute by Subject "Macrophages"
Now showing items 1-3 of 3
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ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells.
(2014-12-15)Cancer stem cells (CSC) are thought to play a major role in the development and metastatic progression of pancreatic ductal adenocarcinoma (PDAC), one of the deadliest solid tumors. Likewise, the tumor microenvironment ... -
A role for macrophages under cytokine control in mediating resistance to ADI-PEG20 (pegargiminase) in ASS1-deficient mesothelioma
(Springer, 2023-04-03)Background Pegylated arginine deiminase (ADI-PEG20; pegargiminase) depletes arginine and improves survival outcomes for patients with argininosuccinate synthetase 1 (ASS1)-deficient malignant pleural mesothelioma (MPM). ...