Browsing Barts Cancer Institute by Subject "Cytokinesis"

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    • PKCɛ switches Aurora B specificity to exit the abscission checkpoint. 

      Pike, T; Brownlow, N; Kjaer, S; Carlton, J; Parker, PJ (2016-12-22)
      The 'NoCut', or Aurora B abscission checkpoint can be activated if DNA is retained in the cleavage furrow after completion of anaphase. Checkpoint failure leads to incomplete abscission and a binucleate outcome. These ...