Browsing Barts Cancer Institute by Subject "Active Transport, Cell Nucleus"

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    • Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells. 

      Sundaresan, S; Meininger, CA; Kang, AJ; Photenhauer, AL; Hayes, MM; Sahoo, N; Grembecka, J; Cierpicki, T; Ding, L; Giordano, TJ (2017-12)
      BACKGROUND & AIMS: The multiple endocrine neoplasia, type 1 (MEN1) locus encodes the nuclear protein and tumor suppressor menin. MEN1 mutations frequently cause neuroendocrine tumors such as gastrinomas, characterized by ...