Browsing Barts Cancer Institute by Title
Now showing items 386-405 of 1159
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Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells.
(2017-12)BACKGROUND & AIMS: The multiple endocrine neoplasia, type 1 (MEN1) locus encodes the nuclear protein and tumor suppressor menin. MEN1 mutations frequently cause neuroendocrine tumors such as gastrinomas, characterized by ... -
GCT-30 Surgical management of ovarian germ cell tumours
(2019-09-01) -
Gene expression profiling of breast cancer in Lebanese women
(2016-11-18) -
Generation and Surgical Analysis of Genetic Mouse Models to Study NF-κB-Driven Pathogenesis of Diffuse Large B Cell Lymphoma.
(2021)Enforced activation of NF-κB signaling can be achieved by constitutive NF-κB-inducing kinases, IKK2 and NIK, or via lymphoma-associated mutants of MYD88, CARD11, and CD79B. In order to model Diffuse Large B Cell Lymphoma ... -
Generation of neighbor-labeling cells to study intercellular interactions in vivo.
(Springer Nature, 2020-12-11)Understanding cell-cell interactions is critical in most, if not all, research fields in biology. Nevertheless, studying intercellular crosstalk in vivo remains a relevant challenge, due mainly to the difficulty in spatially ... -
Genetic and immune landscape evolution in MMR-deficient colorectal cancer.
(2023-11-15)Mismatch repair-deficient (MMRd) colorectal cancers (CRCs) have high mutation burdens, which make these tumours immunogenic and many respond to immune checkpoint inhibitors. The MMRd hypermutator phenotype may also promote ... -
Genetic heterogeneity highlighted by differential FDG-PET response in diffuse large B-cell lymphoma.
(Ferrata Storti Foundation, 2020-04-09)