Browsing Barts Cancer Institute by Title
Now showing items 1075-1094 of 1159
-
Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor?
(2018-01-15)Cadherin-17 (CDH17) has been implicated as protumorigenic for many years, but mechanisms have been unclear. A Spanish team has generated antibodies to an RGD motif in CDH17 that inhibits integrin α2β1 binding to CDH17 and ... -
Targeting FGFR signalling to disrupt cellular cross-talk in pancreatic cancer
(Elsevier, 2020-12-01) -
Targeting inflammatory cytokines in cancer
(2014-11) -
Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer.
(2021)A growing body of literature links events associated with the progression and severity of immunity and inflammatory disease with the composition of the tissue extracellular matrix as defined by the matrisome. One protein ... -
TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.
(2018-05-10)TGF-β/Activin induces epithelial-to-mesenchymal transition and stemness in pancreatic ductal adenocarcinoma (PDAC). However, the microRNAs (miRNAs) regulated during this response have remained yet undetermined. Here, we ...