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dc.contributor.authorRodini, COen_US
dc.contributor.authorLopes, NMen_US
dc.contributor.authorLara, VSen_US
dc.contributor.authorMackenzie, ICen_US
dc.date.accessioned2018-03-13T17:32:42Z
dc.date.available2016-12-31en_US
dc.date.issued2017-11en_US
dc.date.submitted2018-02-09T09:14:26.078Z
dc.identifier.other10.1590/1678-7757-2016-0665
dc.identifier.urihttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000600708&lng=en&tlng=en
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/35244
dc.description.abstractResearch on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma.en_US
dc.description.sponsorshipThe authors would like to thank FAPESP (São Paulo Research Foundation, Grants #2013/07245-9 and #2015/00101-7) for the financial supporten_US
dc.format.extent708 - 715en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofJ Appl Oral Scien_US
dc.rightsCreative Commons Attribution License
dc.subjectCarcinoma, Squamous Cellen_US
dc.subjectCell Differentiationen_US
dc.subjectCell Transformation, Neoplasticen_US
dc.subjectEpithelial-Mesenchymal Transitionen_US
dc.subjectHumansen_US
dc.subjectMouth Neoplasmsen_US
dc.subjectNeoplastic Stem Cellsen_US
dc.titleOral cancer stem cells - properties and consequences.en_US
dc.typeArticle
dc.rights.holder2017 The Authors.
dc.identifier.doi10.1590/1678-7757-2016-0665en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/29211293en_US
pubs.issue6en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume25en_US
dcterms.dateAccepted2016-12-31en_US


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