Browsing Mathematics by Subject "Plasmodium falciparum"
Now showing items 1-6 of 6
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Estimating the most efficient allocation of interventions to achieve reductions in Plasmodium falciparum malaria burden and transmission in Africa: a modelling study.
(2016-07)BACKGROUND: Reducing the burden of malaria is a global priority, but financial constraints mean that available resources must be allocated rationally to maximise their effect. We aimed to develop a model to estimate the ... -
The interaction between seasonality and pulsed interventions against malaria in their effects on the reproduction number.
(2015-01)The basic reproduction number (R0) is an important quantity summarising the dynamics of an infectious disease, as it quantifies how much effort is needed to control transmission. The relative change in R0 due to an ... -
Modelling population-level impact to inform target product profiles for childhood malaria vaccines.
(2018-07-13)BACKGROUND: The RTS,S/AS01 vaccine for Plasmodium falciparum malaria demonstrated moderate efficacy in 5-17-month-old children in phase 3 trials, and from 2018, the vaccine will be evaluated through a large-scale pilot ... -
Modelling the benefits of long-acting or transmission-blocking drugs for reducing Plasmodium falciparum transmission by case management or by mass treatment.
(2017-08-16)BACKGROUND: Anti-malarial drugs are an important tool for malaria control and elimination. Alongside their direct benefit in the treatment of disease, drug use has a community-level effect, clearing the reservoir of infection ... -
Mosquito feeding behavior and how it influences residual malaria transmission across Africa.
(2019-07-23)The antimalarial efficacy of the most important vector control interventions-long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS)-primarily protect against mosquitoes' biting people when they are in ... -
Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa.
(2018-11-26)Indoor residual spraying (IRS) is an important part of malaria control. There is a growing list of insecticide classes; pyrethroids remain the principal insecticide used in bednets but recently, novel non-pyrethroid IRS ...