Browsing Centre for Cancer Prevention by Author "Quarantotti, V"
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Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis
Stojic, L; Lun, A; Mangei, J; Mascalchi, P; Quarantotti, V; Barr, A; Bakal, C; Marioni, J; Gergely, F; Odom, D (2017-12-15)<h4>ABSTRACT</h4> Loss-of-function (LOF) methods, such as RNA interference (RNAi), antisense oligonucleotides or CRISPR-based genome editing, provide unparalleled power for studying the biological function of genes of ...