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    • Evaluating aziridinyl nitrobenzamide compounds as leishmanicidal prodrugs 

      Voak, AA; Seifert, K; Helsby, NA; WILKINSON, SR (2014-01)
      Many of the nitroaromatic agents used in medicine function as prodrugs and must undergo activation before exerting their toxic effects. In most cases this is catalysed by FMN-dependent type I nitroreductases (NTRs), a class ...