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Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials.
(2017-01)
Background: The local injection of novel cardioprotective study drugs prior to percutaneous coronary intervention could cause embolisation of thrombus, resulting in increased reperfusion injury and subsequent infarct size. ...
Development of a Novel Multipenicillin Assay and Assessment of the Impact of Analyte Degradation: Lessons for Scavenged Sampling in Antimicrobial Pharmacokinetic Study Design.
(2018-01)
Penicillins are widely used to treat infections in children; however, the evidence is continuing to evolve in defining the optimal dosing. Modern pediatric pharmacokinetic study protocols frequently favor opportunistic, ...
Plan S: In service or disservice to society?
(Oxford University Press, 2019-03-21)
The controversial plan for scientific research publications to be published in compliant Open Access Journals or on compliant Open Access Platforms is discussed. The article has been co-published with permission in European ...
Weather, day length and physical activity in older adults: Cross-sectional results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Norfolk Cohort.
(2017)
BACKGROUND: A wide range of environmental factors have been related to active ageing, but few studies have explored the impact of weather and day length on physical activity in older adults. We investigate the cross-sectional ...
NSAIDs for high-risk patients: none, celecoxib, or naproxen?
(Elsevier/Science Direct, 2017-06-17)
Godot-like, the all-round safe and effective oral anti-inflammatory drug is awaited. Meantime, substantial effort is devoted to discovering how the existing imperfect non-steroidal anti-inflammatory drugs (NSAIDs) might ...