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Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.
(2018-07-01)
Over the last decade, genome-wide association studies (GWAS) have propelled the discovery of thousands of loci associated with complex diseases. The focus is now turning toward the function of these association signals, ...
Sodium Nitrite-Mediated Cardioprotection in Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A Cost-Effectiveness Analysis.
(2019-03)
OBJECTIVES:: In the follow-up of patients in a trial of intracoronary sodium nitrite given during primary percutaneous coronary intervention (PCI) after acute myocardial infarction (AMI), we found a reduction in the incidence ...
Launch of mini-reviews in hot topics.
(2018-07)
A critical role for the ATP-sensitive potassium channel subunit KIR6.1 in the control of cerebral blood flow.
(2018-06-04)
KIR6.1 (KCNJ8) is a subunit of ATP sensitive potassium channel (KATP) that plays an important role in the control of peripheral vascular tone and is highly expressed in brain contractile cells (vascular smooth muscle cells ...