Browsing Centre for Clinical Pharmacology by Subject "stroke"
Now showing items 1-6 of 6
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Influence of Genetic Variation in PDE3A on Endothelial Function and Stroke
(Wolters Kluwer Health, on behalf of the American Heart Association, Inc., 2019-12-23)We aimed to characterize the genetics of endothelial function and how this influences risk for cardiovascular diseases such as ischemic stroke. We integrated genetic data from a study of ultrasound flow-mediated dilatation ... -
Long-Term Incidence of Stroke and Dementia in ASCOT.
(Wolters Kluwer Health, Inc on behalf of the American Heart Association, Inc, 2021-07-01)BACKGROUND AND PURPOSE: Management of stroke risk factors might reduce later dementia. In ASCOT (Anglo-Scandinavian Outcome Trial), we determined whether dementia or stroke were associated with different blood pressure ... -
Proposed Standardized Neurological Endpoints for Cardiovascular Clinical Trials: An Academic Research Consortium Initiative.
(2017-02-14)Surgical and catheter-based cardiovascular procedures and adjunctive pharmacology have an inherent risk of neurological complications. The current diversity of neurological endpoint definitions and ascertainment methods ... -
Thyroid function affects the risk of stroke via atrial fibrillation: a Mendelian Randomization study.
(Oxford University Press (OUP), 2020-05-06)CONTEXT: Observational studies suggest that variations in normal range thyroid function are associated with cardiovascular diseases. However, it remains to be determined whether these associations are causal or not. ...