Browsing Centre for Clinical Pharmacology by Subject "machine learning"
Now showing items 1-5 of 5
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Gut microbiome-based supervised machine learning for clinical diagnosis of inflammatory bowel diseases.
(American Physiological Society, 2021-01-13)Despite the availability of various diagnostic tests for inflammatory bowel diseases (IBD), misdiagnosis of IBD occurs frequently, and thus there is a clinical need to further improve the diagnosis of IBD. As gut dysbiosis ... -
Reaching the End-Game for GWAS: Machine Learning Approaches for the Prioritization of Complex Disease Loci.
(Frontiers Media, 2020-04-25)Genome-wide association studies (GWAS) have revealed thousands of genetic loci that underpin the complex biology of many human traits. However, the strength of GWAS - the ability to detect genetic association by linkage ... -
Variable selection and risk prediction using a penalised modelling framework for high-dimensional data in a nested matched case-control design
(https://rss.org.uk/training-events/conference2022/, 2022-09-12)In a matched case-control (MCC) study, each subject with the outcome of interest (case) is matched with m subjects without the outcome (control) from the same cohort (often called a 1:m nested MCC). This design is efficient ...