Browsing Centre for Clinical Pharmacology by Subject "Vascular smooth muscle cells"
Now showing items 1-4 of 4
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Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling.
(Oxford University Press, 2021-02-18)AIM: Pathological arterial remodelling including neointimal hyperplasia and atherosclerosis is the main underlying cause for occluding arterial diseases. Cezanne is a novel deubiquitinating enzyme, functioning as a NF-кB ... -
Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease.
(2019-01)During atherosclerosis, the gradual accumulation of lipids into the subendothelial space of damaged arteries results in several lipid modification processes followed by macrophage uptake in the arterial wall. The way in ... -
Neutrophil Elastase Promotes Neointimal Hyperplasia by Targeting TLR4-NFкB Signalling.
(Wiley, 2021-06-02)BACKGROUND AND PURPOSE: Neointimal hyperplasia (NIH) is the fundamental cause for vascular diseases, and vascular smooth muscle cell (VSMC) dysregulation has been widely implicated in NIH. Neutrophil elastase (NE) has been ...