Browsing Centre for Clinical Pharmacology by Subject "Nitric Oxide"
Now showing items 1-3 of 3
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The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway.
(2020-07)In contrast to nitric oxide, which has well established and important roles in the regulation of blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary system, and the inflammation response ... -
NOS2 and <i>S</i>-nitrosothiol signaling induces DNA hypomethylation and LINE-1 retrotransposon expression.
(2022-05)Inducible nitric oxide synthase (NOS2) produces high local concentrations of nitric oxide (NO), and its expression is associated with inflammation, cellular stress signals, and cellular transformation. Additionally, NOS2 ... -
Sex differences in the nitrate-nitrite-NO• pathway: Role of oral nitrate-reducing bacteria.
(2018-10)Oral reduction of nitrate to nitrite is dependent on the oral microbiome and is the first step of an alternative mammalian pathway to produce nitric oxide in humans. Preliminary evidence suggests important sex differences ...