Browsing Centre for Clinical Pharmacology by Subject "Myeloid Cells"
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Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
(2018-08-06)Cholesterol homeostasis has a pivotal function in regulating immune cells. Here we show that apolipoprotein E (apoE) deficiency leads to the accumulation of cholesterol in the cell membrane of dendritic cells (DC), resulting ...