Browsing Centre for Clinical Pharmacology by Subject "Gout"
Now showing items 1-2 of 2
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Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial.
(2022-10-08)BACKGROUND: Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous studies have shown that allopurinol has positive effects on several cardiovascular parameters. The ALL-HEART study aimed to ... -
Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism
(BMC, 2021-05-24)Objective: To evaluate the taxonomic composition of the gut microbiome in gout patients with and without tophi formation, and predict bacterial functions that might have an impact on urate metabolism. Methods: Hypervariable ...