Browsing Centre for Clinical Pharmacology by Subject "CRISPR"
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CRISPR/dCas9 DNA methylation editing is heritable during human hematopoiesis and shapes immune progeny.
(2023-08-22)Aging is associated with an abnormal increase in DNA methylation (DNAm) in human gene promoters, including in bone marrow stem cells. DNAm patterns are further perturbed in hematological malignancies such as acute myeloid ...