Browsing Centre for Clinical Pharmacology by Subject "1p21.3"
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MIR137 is the key gene mediator of the syndromic obesity phenotype of patients with 1p21.3 microdeletions.
(2016)BACKGROUND: Deletions in the long arm of chromosome 1 have been described in patients with a phenotype consisting primarily of obesity, intellectual disability and autism-spectrum disorder. The minimal region of overlap ...