Browsing Centre for Clinical Pharmacology by Author "Yellon, DM"
Now showing items 1-3 of 3
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Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.
Hausenloy, DJ; Kharbanda, RK; Møller, UK; Ramlall, M; Aarøe, J; Butler, R; Bulluck, H; Clayton, T; Dana, A; Dodd, M (2019-10-19)BACKGROUND: Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing ... -
The GTN patch: a simple and effective new approach to cardioprotection?
Yellon, DM; He, Z; Khambata, R; Ahluwalia, A; Davidson, SM (2018-04-17)There remains a significant un-met need to reduce the extent of myocardial injury caused by ischaemia and reperfusion injury in patients experiencing an ST-elevation MI. Although nitric oxide is central to many cardioprotective ... -
Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection.
Heusch, G; Andreadou, I; Bell, R; Bertero, E; Botker, H-E; Davidson, SM; Downey, J; Eaton, P; Ferdinandy, P; Gersh, BJ (2023-11)The present review summarizes the beneficial and detrimental roles of reactive oxygen species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the continued need for cardioprotection beyond ...